Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 8/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560889 | 0.92 | MAPK14 (0.49) | MAPK14CETPMRGPRX4 | |
| SCHEMBL9560407 | 0.88 | LMNA (0.40) | CETPPPARGPPARALMNAALDH1A1 | |
| SCHEMBL9560497 | 0.88 | ALDH1A1 (0.41) | CETPPPARGPPARALMNAMRGPRX4 | |
| SCHEMBL9560424 | 0.86 | MAPK14 (0.40) | MAPK14CETPCNR1TRPV1PPARG | |
| SCHEMBL9560888 | 0.82 | ALDH1A1 (0.39) | CETPPPARGPPARALMNAALDH1A1 | |
| SCHEMBL9560883 | 0.82 | ALDH1A1 (0.39) | CETPPPARGPPARALMNAALDH1A1 | |
| SCHEMBL9560369 | 0.82 | MAOB (0.44) | CETPPPARGPPARALMNAKCNH2 | |
| SCHEMBL9561097 | 0.82 | MAPK14 (0.44) | MAPK14CETPMRGPRX4 | |
| SCHEMBL9560466 | 0.81 | ALDH1A1 (0.48) | MAPK14CETPLMNAALDH1A1 | |
| SCHEMBL9785758 | 0.81 | CETP (0.43) | MAPK14CETPCNR1TRPV1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |