Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.30 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560881 | 0.86 | MAPK14 (0.39) | MAPK14KIF11RXRBRXRARXRG | |
| SCHEMBL10837257 | 0.86 | MAPK14 (0.39) | MAPK14KIF11RXRBRXRARXRG | |
| SCHEMBL10837214 | 0.85 | MAPK14 (0.38) | MAPK14KIF11RXRBRXRARXRG | |
| SCHEMBL9561293 | 0.85 | LMNA (0.35) | MRGPRX4L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9560787 | 0.85 | L3MBTL1 (0.34) | MRGPRX4L3MBTL1SMN1; SMN2TTR | |
| SCHEMBL9560696 | 0.83 | TACR1 (0.36) | NPC1RAB9APOLBMRGPRX4KMT2A | |
| SCHEMBL9560804 | 0.82 | TTR (0.39) | RAB9AL3MBTL1SMN1; SMN2TTR | |
| SCHEMBL9560860 | 0.82 | CHRM5 (0.36) | MAPK14KIF11MRGPRX4TTR | |
| SCHEMBL9560383 | 0.81 | TTR (0.34) | NPC1RAB9ATTR | |
| SCHEMBL9560321 | 0.80 | MAPT (0.40) | KIF11L3MBTL1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |