Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560787 | 0.90 | L3MBTL1 (0.34) | SLC6A4MRGPRX4TACR1TTR | |
| SCHEMBL9561293 | 0.90 | LMNA (0.35) | LTA4HEPHX2SLC6A4MRGPRX4TACR1 | |
| SCHEMBL9560804 | 0.90 | TTR (0.39) | LTA4HTTR | |
| SCHEMBL9560696 | 0.88 | TACR1 (0.36) | MRGPRX4TACR1TTRFFAR4 | |
| SCHEMBL9560321 | 0.88 | MAPT (0.40) | LTA4HSLC6A4SLC6A2SLC6A3KIF11 | |
| SCHEMBL9560383 | 0.87 | TTR (0.34) | LTA4HEPHX2TACR1TTR | |
| SCHEMBL9558208 | 0.86 | SLC6A4 (0.39) | CHRM5LTA4HEPHX2SLC6A4SLC6A2 | |
| SCHEMBL9561340 | 0.85 | LTA4H (0.38) | CHRM5LTA4HEPHX2SLC6A4SLC6A2 | |
| SCHEMBL9560464 | 0.85 | MAPK14 (0.47) | CHRM5LTA4HEPHX2MAPK14CETP | |
| SCHEMBL9637902 | 0.83 | L3MBTL1 (0.33) | LTA4HMRGPRX4TACR1TTRHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |