Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883642 | 0.84 | KMT2A (0.47) | ALDH1A1TDP1ICAM1SELEKMT2A | |
| SCHEMBL9505653 | 0.81 | KMT2A (0.43) | ALDH1A1TDP1KMT2ARAB9AMAPT | |
| SCHEMBL2791741 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1ICAM1SELEKMT2A | |
| SCHEMBL28956680 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TDP1ICAM1SELEKMT2A | |
| SCHEMBL5831972 | 0.79 | ELANE (0.56) | ALDH1A1TDP1KMT2AMAPTKDM4E | |
| SCHEMBL3903145 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TDP1KMT2ARAB9AMAPT | |
| SCHEMBL6398442 | 0.78 | THRB (0.55) | ALDH1A1TDP1KMT2ARAB9AMAPT | |
| SCHEMBL11768896 | 0.78 | KMT2A (0.49) | ALDH1A1TDP1KMT2AMAPTKDM4E | |
| Urea SCHEMBL7262146 | 0.76 | ALDH1A1 (0.65) | ALDH1A1TDP1ICAM1SELEPARP10 | |
| SCHEMBL72231 | 0.76 | MAPT (0.59) | ALDH1A1TDP1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198452-A | Leukotriene antagonist, lipoxygenase or cyclooxygenase inhibitors, antihistamines or antiallergens | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0466125-A2 | Styryl compounds and their pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |