Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 8/20 | 0.36 |
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560847 | 1.00 | MAPK14 (0.41) | MAPK14RXRBNPC1RAB9ARXRA | |
| SCHEMBL9560570 | 0.84 | L3MBTL1 (0.38) | SMN1; SMN2GAAL3MBTL1MRGPRX4LPAR1 | |
| SCHEMBL9560573 | 0.84 | L3MBTL1 (0.38) | SMN1; SMN2GAAL3MBTL1MRGPRX4LPAR1 | |
| SCHEMBL9560896 | 0.82 | MAPK14 (0.39) | MAPK14RXRBRXRARXRGMRGPRX4 | |
| SCHEMBL9560901 | 0.82 | MAPK14 (0.39) | MAPK14RXRBRXRARXRGMRGPRX4 | |
| SCHEMBL9560799 | 0.81 | RAB9A (0.38) | MAPK14RXRBNPC1RAB9ARXRA | |
| SCHEMBL9560802 | 0.81 | RAB9A (0.38) | MAPK14RXRBNPC1RAB9ARXRA | |
| SCHEMBL9561171 | 0.81 | LPAR1 (0.36) | NPC1RAB9AGAALPAR1LPAR5 | |
| SCHEMBL9561164 | 0.81 | LPAR1 (0.36) | NPC1RAB9AGAALPAR1LPAR5 | |
| SCHEMBL9560746 | 0.73 | MAPK14 (0.37) | MAPK14RXRBNPC1RAB9ARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |