Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561332 | 1.00 | MAPK14 (0.44) | MAPK14TRPV1MRGPRX4CETPCNR1 | |
| SCHEMBL9560817 | 0.92 | MAPK14 (0.52) | MAPK14MRGPRX4CETPGRIN2B | |
| SCHEMBL9560811 | 0.92 | MAPK14 (0.52) | MAPK14MRGPRX4CETPGRIN2B | |
| SCHEMBL9560901 | 0.80 | MAPK14 (0.39) | MAPK14TRPV1MRGPRX4CETPGRIN2B | |
| SCHEMBL9560896 | 0.80 | MAPK14 (0.39) | MAPK14TRPV1MRGPRX4CETPGRIN2B | |
| SCHEMBL9561472 | 0.80 | LTA4H (0.46) | MAPK14MRGPRX4CETPLMNA | |
| SCHEMBL9561470 | 0.80 | LTA4H (0.46) | MAPK14MRGPRX4CETPLMNA | |
| SCHEMBL9560570 | 0.77 | L3MBTL1 (0.38) | MRGPRX4LMNAALDH1A1CYP2C9PTGER4 | |
| SCHEMBL9560573 | 0.77 | L3MBTL1 (0.38) | MRGPRX4LMNAALDH1A1CYP2C9PTGER4 | |
| SCHEMBL9493701 | 0.75 | ALDH1A1 (0.38) | MAPK14TRPV1CETPGRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |