SCHEMBL9561371

SCHEMBL9561371

C=C(C)c1cccc(CC(C)OOC(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.46
FOLH1 Q04609 6/20 0.36
ALDH1A1 P00352 3/20 0.35
ANPEP P15144 1/20 0.34
ENPEP Q07075 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675590 0.83 TAAR1 (0.40) SLC7A5MAPT
SCHEMBL15161841 0.77 SIGMAR1 (0.47) KMT2A
SCHEMBL9814342 0.76 SLC7A5 (0.41) SLC7A5FOLH1ANPEPENPEP
SCHEMBL28097746 0.76 PNMT (0.53) SLC7A5ANPEPENPEP
SCHEMBL30786391 0.75 ALDH1A1 (0.41) ALDH1A1KDM4EMAPT
SCHEMBL8680649 0.74 SLC7A5 (0.40) SLC7A5FOLH1ANPEPENPEP
SCHEMBL15896437 0.74 SLC7A5 (0.50) SLC7A5FOLH1ANPEPENPEPPPARA
SCHEMBL19240347 0.73 SLC7A5 (0.40) SLC7A5ALDH1A1KDM4EMAPTKMT2A
SCHEMBL25381410 0.73 HMGCR (0.32)
SCHEMBL22494133 0.73 SLC6A4 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5231249-A Olefin polymer crosslinked with (tert-butylperoxyisopropyl)-isopropylbenzene THE FURUKAWA ELECTRIC CO., LTD. (JP) 1993-07-27 US disclosed
EP-0469155-A1 OLEFINIC RESIN COMPOSITION FOR POWER CABLE, AND POWER CABLE AND JUNCTION THEREOF MADE FROM SAID COMPOSITION THE FURUKAWA ELECTRIC CO., LTD. (JP) 1992-02-05 EP disclosed