Diphenylamine

Diphenylamine

SCHEMBL9561449

c1ccc(CCc2ccc(CCc3ccccc3)cc2)cc1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.63
ALDH1A1 P00352 5/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
ALOX12 P18054 3/20 0.60
MAPK1 P28482 2/20 0.60
ALOX15 P16050 2/20 0.60
TSHR P16473 1/20 0.60
PTGS1 P23219 1/20 0.60
SLC6A2 P23975 1/20 0.60
PTGS2 P35354 1/20 0.60
HTR2B P41595 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
MAOA P21397 2/20 0.54
MAOB P27338 2/20 0.54
MAPT P10636 4/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
AR P10275 1/20 0.52
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932079 0.97 ALDH1A1 (0.65) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1
Diphenylamine SCHEMBL9782686 0.97 HSD17B10 (0.67) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1
SCHEMBL2355458 0.95 ALDH1A1 (0.60) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1
Diphenylamine SCHEMBL9561950 0.88 MAPT (0.58) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1
SCHEMBL12506236 0.83 MAOB (0.72) HSD17B10ALDH1A1ALOX12ALOX15TDP1
SCHEMBL55138 0.83 MAOB (0.72) HSD17B10ALDH1A1ALOX12ALOX15TDP1
SCHEMBL19187359 0.82 ALDH1A1 (0.65) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1
SCHEMBL25557237 0.82 ALDH1A1 (0.65) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1
SCHEMBL14707934 0.81 ALDH1A1 (0.56) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1
SCHEMBL3614137 0.81 TDP1 (0.62) HSD17B10ALDH1A1L3MBTL1ALOX12MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1085950-A None JP disclosed
US-5250377-A Durable, highly photosensitive RICOH COMPANY, LTD. (JP) 1993-10-05 US disclosed
US-5159087-A High photosensitivity, durability RICOH COMPANY, LTD. (JP) 1992-10-27 US disclosed
US-4886846-A CHARGE TRANSFER COMPOUNDS RICOH COMPANY, LTD. (JP) 1989-12-12 US disclosed