Diphenylamine

Diphenylamine

SCHEMBL9561950

c1ccc(CCc2cccc(CCc3ccccc3)c2)cc1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
ALDH1A1 P00352 5/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
AR P10275 1/20 0.58
HSD17B10 Q99714 3/20 0.55
MAOA P21397 3/20 0.54
MAOB P27338 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 2/20 0.52
ALOX12 P18054 2/20 0.52
ALOX15 P16050 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
GAA P10253 3/20 0.48
CYP3A4 P08684 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL9782686 0.91 HSD17B10 (0.67) MAPTALDH1A1MEN1KMT2AAR
Diphenylamine SCHEMBL9561449 0.88 HSD17B10 (0.63) MAPTALDH1A1MEN1KMT2AAR
SCHEMBL6932079 0.86 ALDH1A1 (0.65) MAPTALDH1A1MEN1KMT2AAR
SCHEMBL2355458 0.83 ALDH1A1 (0.60) MAPTALDH1A1MEN1KMT2AHSD17B10
SCHEMBL1406273 0.79 MAPT (0.56) MAPTALDH1A1MEN1KMT2AAR
SCHEMBL24548251 0.79 ABCG2 (0.48) MAPTALDH1A1MEN1KMT2AAR
SCHEMBL28208630 0.78 ALDH1A1 (0.78) MAPTALDH1A1MEN1KMT2AAR
SCHEMBL4648373 0.77 ALDH1A1 (0.58) ALDH1A1HSD17B10MAOAMAOBTDP1
SCHEMBL24548277 0.77 HPGD (0.68) MAPTALDH1A1MEN1KMT2AMAOA
SCHEMBL19008844 0.77 HIF1A (0.55) MAPTALDH1A1MEN1KMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250377-A Durable, highly photosensitive RICOH COMPANY, LTD. (JP) 1993-10-05 US disclosed
US-5159087-A High photosensitivity, durability RICOH COMPANY, LTD. (JP) 1992-10-27 US disclosed
US-4886846-A CHARGE TRANSFER COMPOUNDS RICOH COMPANY, LTD. (JP) 1989-12-12 US disclosed