SCHEMBL2355458

SCHEMBL2355458

c1ccc(CCc2ccc(Nc3ccc(CCc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
HSD17B10 Q99714 3/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
ALOX12 P18054 3/20 0.60
MAPK1 P28482 2/20 0.60
ALOX15 P16050 2/20 0.60
TSHR P16473 2/20 0.60
PTGS1 P23219 2/20 0.60
SLC6A2 P23975 2/20 0.60
PTGS2 P35354 1/20 0.60
HTR2B P41595 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
SIRT2 Q8IXJ6 1/20 0.55
MAOA P21397 3/20 0.54
MAOB P27338 3/20 0.54
MAPT P10636 2/20 0.52
LMNA P02545 2/20 0.52
MEN1 O00255 1/20 0.52
GAA P10253 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932079 0.97 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1
Diphenylamine SCHEMBL9561449 0.95 HSD17B10 (0.63) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1
Diphenylamine SCHEMBL9782686 0.92 HSD17B10 (0.67) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1
SCHEMBL284700 0.84 CALM1 (0.63) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1
SCHEMBL6931652 0.84 RAB9A (0.51) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1
Diphenylamine SCHEMBL9561950 0.83 MAPT (0.58) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1
SCHEMBL55138 0.83 MAOB (0.72) ALDH1A1HSD17B10ALOX12ALOX15TDP1
SCHEMBL12506236 0.83 MAOB (0.72) ALDH1A1HSD17B10ALOX12ALOX15TDP1
SCHEMBL19187359 0.82 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1
SCHEMBL14707934 0.81 ALDH1A1 (0.56) ALDH1A1HSD17B10L3MBTL1ALOX12MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8552097-B2 Polymer vulcanizate and process for the production thereof LANXESS DEUTSCHLAND GMBH (DE) 2013-10-08 US claimed
US-20090163631-A1 POLYMER VULCANIZATE AND PROCESS FOR THE PRODUCTION THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2009-06-25 US claimed
EP-2065438-A2 Improved polymer vulcanizate and process for the production thereof Lanxess Deutschland GmbH (DE) 2009-06-03 EP claimed
EP-0585934-B1 Method to run a compressor-heatpump or refrigerationplant with ammonia as refrigerant LINDE AG (DE) 1998-04-22 EP claimed
US-5413728-A Process for operating a compressor heat pump or a compressor refrigeration system in which ammonia is used as the refrigerant RHEIN CHEMIE RHEINAU GMBH (DE) 1995-05-09 US claimed
EP-0585934-A1 Method to run a compressor-heatpump or refrigerationplant with ammonia as refrigerant Linde Aktiengesellschaft (DE) 1994-03-09 EP claimed
WO-2023237771-A1 HALS AS ANTI-MICROBIAL ADDITIVES IN FREE-RADICAL SYSTEMS ARKEMA FRANCE (FR) 2023-12-14 WO disclosed
EP-4045564-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF Promerus, LLC (US) 2022-08-24 EP disclosed
EP-3830233-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS Milliken & Company (US) 2021-06-09 EP disclosed
WO-2021076131-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2021-04-22 WO disclosed
WO-2020023897-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY (US) 2020-01-30 WO disclosed
CN-109890877-A Additive masterbatch composition based on semicrystalline polyolefins 陶氏环球技术有限责任公司 2019-06-14 CN disclosed
US-8697618-B2 Method of using ionic liquids to improve the lubrication of chains, steel belts, wheel bearings, roller bearings, and electric motors KLüBER LUBRICATION MüNCHEN KG (DE) 2014-04-15 US disclosed
EP-2065438-A2 Improved polymer vulcanizate and process for the production thereof Lanxess Deutschland GmbH (DE) 2009-06-03 EP disclosed
EP-1930400-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2008-06-11 EP disclosed
US-6184262-B1 Benzotriazole stabilizers for polyols and polyurethane foam R. T. VANDERBILT COMPANY, INC. 2001-02-06 US disclosed
EP-0839861-A2 Benzotriazole stabilizers for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1998-05-06 EP disclosed
EP-0585934-B1 Method to run a compressor-heatpump or refrigerationplant with ammonia as refrigerant LINDE AG (DE) 1998-04-22 EP disclosed
US-5413728-A Process for operating a compressor heat pump or a compressor refrigeration system in which ammonia is used as the refrigerant RHEIN CHEMIE RHEINAU GMBH (DE) 1995-05-09 US disclosed
EP-0585934-A1 Method to run a compressor-heatpump or refrigerationplant with ammonia as refrigerant Linde Aktiengesellschaft (DE) 1994-03-09 EP disclosed