SCHEMBL6932079

SCHEMBL6932079

c1ccc(CCc2ccc(Nc3ccccc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.65
HSD17B10 Q99714 5/20 0.65
L3MBTL1 Q9Y468 4/20 0.65
ALOX12 P18054 3/20 0.65
TSHR P16473 3/20 0.65
TDP1 Q9NUW8 3/20 0.65
MAPK1 P28482 2/20 0.65
ALOX15 P16050 2/20 0.65
PTGS1 P23219 1/20 0.65
SLC6A2 P23975 1/20 0.65
PTGS2 P35354 1/20 0.65
HTR2B P41595 1/20 0.65
MAPT P10636 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
LMNA P02545 2/20 0.55
GAA P10253 1/20 0.55
SIRT2 Q8IXJ6 1/20 0.53
CYP3A4 P08684 4/20 0.52
MAOA P21397 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL9561449 0.97 HSD17B10 (0.63) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
SCHEMBL2355458 0.97 ALDH1A1 (0.60) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
Diphenylamine SCHEMBL9782686 0.95 HSD17B10 (0.67) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
Diphenylamine SCHEMBL9561950 0.86 MAPT (0.58) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
SCHEMBL19187359 0.85 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
SCHEMBL25557237 0.85 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
SCHEMBL3614137 0.84 TDP1 (0.62) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
SCHEMBL14707934 0.84 ALDH1A1 (0.56) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
SCHEMBL9844921 0.84 TDP1 (0.62) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR
SCHEMBL30266145 0.82 L3MBTL1 (0.73) ALDH1A1HSD17B10L3MBTL1ALOX12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023377-B1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEM CO INC (US) 2003-12-03 EP claimed
US-6348514-B1 ISOCYANATE REACTIVE COMPOSITION WITH STABILIZER OF METHYL 3-(4-HYDROXY-3,5-DI-TERT-BUTYLPHENYL)PROPIONATE UNIROYAL CHEMICAL COMPANY, INC. 2002-02-19 US claimed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
US-5571453-A PHOTOSTABILITY USING REACTION PRODUCT OF DIPHENYLAMINE, ISOBUTYLENE AND DIISOBUTYLENE AND STERICALLY HINDERED PHENOL AND TRIHYDROCARBYL PHOSPHITE UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-11-05 US disclosed
WO-1996012760-A2 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-05-02 WO disclosed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP disclosed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO disclosed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US disclosed
EP-0399142-B1 Stabilizer compositions for polyols and polyurethane foam VANDERBILT CO R T (US) 1994-01-26 EP disclosed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US disclosed
EP-0556612-A1 Synergistic stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1993-08-25 EP disclosed
US-5156762-A 2,6-Di-tert-butyl-4-sec-butylphenol, phenothiazine or alkyl-substitued derivative, and reaction product of styrene, diisobutylene and diphenylamine R. T. VANDERBILT COMPANY, INC. (US) 1992-10-20 US disclosed
US-5143943-A 2,6-di-tert-butyl-4-sec-butylphenol; reaction product of styrene, diphenylamine, and diisobutylene; and phenothiazine compound; discoloration inhibition R. T. VANDERBILT COMPANY, INC. (US) 1992-09-01 US disclosed
EP-0399142-A2 Stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, INC. (US) 1990-11-28 EP disclosed
US-4933374-A 2,6-DI-TERT-BUTYL-4-SEC-BUTYLPHENOL, REACTION PRODUCT OF DIISOBUTYLENE, STYRENE AND DIPHENYLAMINE R. T. VANDERBILT COMPANY, INC. (US) 1990-06-12 US disclosed