SCHEMBL9561787

SCHEMBL9561787

Cc1ccc(S(=O)(=O)NCc2cc(-c3ccccc3)c3ccc4c(-c5ccccc5)cc(CNS(=O)(=O)c5ccc(C)cc5)nc4c3n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.52
CA9 Q16790 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ALDH1A1 P00352 2/20 0.49
PKM P14618 1/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CYP19A1 P11511 1/20 0.48
THRB P10828 1/20 0.47
CKS1B P61024 1/20 0.47
SKP2 Q13309 1/20 0.47
LMNA P02545 4/20 0.47
HTT P42858 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 2/20 0.47
TSHR P16473 1/20 0.47
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14560804 0.74 SMN1; SMN2 (0.41) CYP1A2CYP3A4L3MBTL1ALDH1A1MEN1
SCHEMBL9561776 0.74 KMT2A (0.61) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL29019313 0.71 CA12 (0.82) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL2183573 0.70 ACACA (0.39) ATML3MBTL1ALDH1A1PKMMEN1
SCHEMBL198318 0.70 CA12 (1.00) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL9305676 0.70 PRMT1 (0.74) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL29530578 0.70 PRMT1 (0.74) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL26054027 0.70 KMT2A (0.65) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL17612274 0.69 CRHR1 (0.46) L3MBTL1ALDH1A1MEN1KMT2ALMNA
SCHEMBL13458726 0.69 KDM4E (0.57) L3MBTL1ALDH1A1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5262526-A Fluorescent compound, complex, reagent, and specific binding assay employing said reagent DOJINDO LABORATORIES (JP) 1993-11-16 US disclosed
EP-0493745-A1 Fluorescent compound, complex, reagent, and specific binding assay employing said reagent DOJINDO LABORATORIES (JP) 1992-07-08 EP disclosed