SCHEMBL2183573

SCHEMBL2183573

CCc1cc(-c2ccccc2)c2ccc3c(-c4ccccc4)cc(CC)nc3c2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 3/20 0.39
ADORA1 P30542 2/20 0.39
ADORA3 P0DMS8 1/20 0.39
ADORA2A P29274 1/20 0.39
HSP90AA1 P07900 1/20 0.38
CRHR1 P34998 1/20 0.38
PDPK1 O15530 1/20 0.38
MAT2A P31153 1/20 0.38
MEN1 O00255 3/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
KMT2A Q03164 3/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 1/20 0.37
MPI P34949 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
PKM P14618 1/20 0.36
USP2 O75604 1/20 0.36
MAPK1 P28482 1/20 0.36
CTNNB1 P35222 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13438959 0.92 CRHR1 (0.46) ACACAADORA1ADORA2AHSP90AA1CRHR1
SCHEMBL12004809 0.89 TOP2A (0.41) ACACAHSP90AA1PDPK1L3MBTL1
SCHEMBL20286674 0.89 MAOA (0.42) ACACAHSP90AA1CRHR1MEN1ALDH1A1
SCHEMBL14560671 0.86 CTSK (0.48) ACACAADORA1ADORA3ADORA2ACRHR1
SCHEMBL1227402 0.83 PSMB5 (0.45) ADORA1ADORA3ADORA2AMEN1KMT2A
SCHEMBL23434559 0.83 ACACA (0.40) ACACAADORA1ADORA3ADORA2APDPK1
SCHEMBL23433400 0.83 ACACA (0.42) ACACAADORA1ADORA3ADORA2AHSP90AA1
SCHEMBL9333851 0.82 CCR1 (0.39) ACACACRHR1MEN1ALDH1A1MAPT
SCHEMBL23434307 0.82 ACACA (0.41) ACACAADORA1ADORA3ADORA2AMEN1
SCHEMBL5394725 0.81 ALDH1A1 (0.44) MEN1ALDH1A1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070248841-A1 Organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2007-10-25 US claimed
EP-1205527-B2 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO (JP) 2020-10-07 EP disclosed
US-20170098785-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2017-04-06 US disclosed
US-9564607-B2 Organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2017-02-07 US disclosed
US-9523031-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2016-12-20 US disclosed
US-20140239282-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-8753757-B2 Organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2014-06-17 US disclosed
US-20110163660-A1 Organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2011-07-07 US disclosed
US-7745988-B2 3, 6-diphenylcarbazole compound and organic electroluminescent device RICOH COMPANY, LIMITED (JP) 2010-06-29 US disclosed
EP-1097981-B1 Organic electroluminescent device SONY CORP (JP) 2010-04-14 EP disclosed
EP-1708547-A1 HOST MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2006-10-04 EP disclosed
US-20060076537-A1 Rhenium compounds ISIS INNOVATION LIMITED (GB) 2006-04-13 US disclosed
US-20060046098-A1 Organic host material for an organic luminescence layer of a carbazole derivative with a glass-transition temperature of 110 degrees C., and a phosphorescent dopant; heat-resistance IDEMITSU KOSAN CO., LTD. (JP) 2006-03-02 US disclosed
US-6979414-B2 laminated interlayer a carbazole derivative; organoluminesce element for automobile use; heat resistant; emits fluorescence even at high temperature IDEMITSU KOSAN CO., LTD. (JP) 2005-12-27 US disclosed
CN-1694591-A Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2005-11-09 CN disclosed
US-20050222429-A1 laminated interlayer a carbazole derivative; organoluminesce element for automobile use; heat resistant; emits fluorescence even at high temperature IDEMITSU KOSAN CO., LTD. (JP) 2005-10-06 US disclosed
US-20050084711-A1 3, 6-Diphenylcarbazole compound and organic electroluminescent device RICOH COMPANY LIMITED (JP) 2005-04-21 US disclosed
US-6660410-B2 Organic luminescence layer having a carbazole derivative with a glass-transition temperature of 110 degrees C. or higher, and a phosphorescent dopant; possible triplet exciton state at room temperature IDEMITSU KOSAN CO., LTD. (JP) 2003-12-09 US disclosed
EP-1205527-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2002-05-15 EP disclosed
US-20020045061-A1 Organic luminescence layer having a carbazole derivative with a glass-transition temperature of 110 degrees C. or higher, and a phosphorescent dopant; possible triplet exciton state at room temperature IDEMITSU KOSAN CO., LTD. 2002-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050084711-A1 3, 6-Diphenylcarbazole compound and organic electroluminescent device OXA1L, MCU, SLC25A21 ACACA 1985/4885ADORA1 2906/4885ADORA3 1487/4885
US-20050222429-A1 laminated interlayer a carbazole derivative; organoluminesce element for automobile use; heat resistant; emits fluorescence even at high temperature IL33, HSF1, WEE1 ACACA 994/4885ADORA1 2811/4885ADORA3 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.