Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptafluorobutyramide SCHEMBL809135 | 0.73 | THRB (0.43) | THRBF2PRSS1PRSS2PRSS3 | |
| Trifluoroacetamide SCHEMBL142 | 0.72 | — | — | |
| Trifluoroacetamide SCHEMBL27678123 | 0.72 | LMNA (0.42) | ALDH1A1LMNAOR51E2TDP1F2 | |
| SCHEMBL27096224 | 0.71 | THRB (0.41) | THRBALDH1A1LMNAOR51E2TDP1 | |
| SCHEMBL808848 | 0.71 | THRB (0.35) | THRBALDH1A1LMNAOR51E2TDP1 | |
| SCHEMBL15803915 | 0.71 | ALDH1A1 (0.33) | ALDH1A1LMNAOR51E2TDP1ACHE | |
| SCHEMBL5704734 | 0.71 | THRB (0.35) | THRBALDH1A1LMNAOR51E2TDP1 | |
| SCHEMBL6740067 | 0.71 | THRB (0.55) | THRBLMNAF2PRSS1PRSS2 | |
| Heptafluorobutyramide SCHEMBL4827051 | 0.71 | THRB (0.42) | THRBF2PRSS1PRSS2PRSS3 | |
| Trifluoroacetamide SCHEMBL5638451 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311028-B1 | A PROCESS FOR BIS (4-AMINOPHENYL) HEXAFLUOROPROPANE | HOECHST CELANESE CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5011997-A | Process for bis(4-aminophenyl)hexafluoropropane | HOECHST CELANESE CORP. (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0311028-A2 | A process for bis (4-aminophenyl) hexafluoropropane | HOECHST CELANESE CORPORATION (US) | 1989-04-12 | — | — | EP | disclosed |