Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.74 |
| ▸ | MMP8 | P22894 | 10/20 | 0.74 |
| ▸ | MMP14 | P50281 | 4/20 | 0.74 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.55 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215459 | 0.83 | MMP9 (0.57) | MMP9MMP8MMP14MMP2CTSS | |
| SCHEMBL2258793 | 0.82 | TGFBR1 (0.57) | MMP9MMP8MMP14 | |
| SCHEMBL346221 | 0.82 | TGFBR1 (0.57) | MMP9MMP8MMP14 | |
| SCHEMBL1629333 | 0.81 | KDM4E (0.55) | MMP9MMP8MEN1KMT2AMAPT | |
| SCHEMBL8988836 | 0.81 | KDM4E (0.55) | MMP9MMP8MEN1KMT2AMAPT | |
| SCHEMBL4953516 | 0.81 | KDM4E (0.55) | MMP9MMP8MEN1KMT2AMAPT | |
| SCHEMBL14264742 | 0.81 | MMP9 (0.70) | MMP9MMP8MMP14GPR139PSMB1 | |
| SCHEMBL8980443 | 0.81 | MMP9 (0.51) | MMP9MMP8MMP14MEN1KMT2A | |
| SCHEMBL14264746 | 0.80 | MMP9 (0.68) | MMP9MMP8MMP14GPR139PSMB1 | |
| SCHEMBL8374049 | 0.79 | FCER2 (0.50) | MMP9MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274167-A | A N-(meth)acryloyl amino acid amide | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |