SCHEMBL346221

SCHEMBL346221

C=C(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.57
MME P08473 7/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NPSR1 Q6W5P4 1/20 0.55
LTA4H P09960 1/20 0.55
NAALAD2 Q9Y3Q0 1/20 0.54
ACE P12821 5/20 0.52
CPA1 P15085 4/20 0.52
ACE2 Q9BYF1 4/20 0.52
MMP9 P14780 1/20 0.51
MMP8 P22894 1/20 0.51
MMP14 P50281 1/20 0.51
FPR2 P25090 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2258793 1.00 TGFBR1 (0.57) TGFBR1MMEL3MBTL1NPSR1LTA4H
SCHEMBL346687 0.88 FOLH1 (0.59) TGFBR1MMENAALAD2ACECPA1
SCHEMBL8021425 0.88 FOLH1 (0.59) TGFBR1MMENAALAD2ACECPA1
SCHEMBL8374049 0.88 FCER2 (0.50) TGFBR1LTA4HMMP9MMP8MMP14
SCHEMBL18550602 0.87 MME (0.59) MMEL3MBTL1NPSR1NAALAD2ACE
SCHEMBL596491 0.87 MME (0.59) MMEL3MBTL1NPSR1LTA4HNAALAD2
SCHEMBL596493 0.87 MME (0.59) MMEL3MBTL1NPSR1LTA4HNAALAD2
SCHEMBL6218963 0.86 ATM (0.62) L3MBTL1
SCHEMBL6215459 0.86 MMP9 (0.57) MMP9MMP8MMP14
SCHEMBL13524950 0.86 ATM (0.62) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096514-B Polymerizable amino acid-based compounds and ophthalmic devices made therefrom 强生视力健公司 2025-06-17 CN claimed
EP-4165015-B9 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-11-27 EP claimed
EP-4165015-B1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-08-07 EP claimed
CN-114096514-A Amino acid based polymerizable compounds and ophthalmic devices made therefrom 强生视力健公司 2022-02-25 CN claimed
EP-3355706-B1 GUM BASES AND CHEWING GUMS USING THERMOSENSITIVE POLYMERS WRIGLEY W M JUN CO (US) 2020-11-04 EP claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-5549807-A Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers THE UNIVERSITY OF CONNECTICUT (US) 1996-08-27 US claimed
US-5238542-A Onto electrically conductive filler THE UNIVERSITY OF CONNECTICUT (US) 1993-08-24 US claimed
JP-57016809-A None JP disclosed
EP-4165015-B9 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-11-27 EP disclosed
EP-4165015-B1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-08-07 EP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
US-20240139078-A1 DENTAL FILLING KIT KURARAY NORITAKE DENTAL INC. (JP) 2024-05-02 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
US-5466357-A THERMOPLASTIC MATRIX PREPREG COMPOSITE PRODUCT THE UNIVERSITY OF CONNECTICUT (US) 1995-11-14 US disclosed
US-5238542-A Onto electrically conductive filler THE UNIVERSITY OF CONNECTICUT (US) 1993-08-24 US disclosed
US-5175254-A Solid phase peptide synthesis using a polyacrylic support in aqueous solution SOCIETE D'EXPANSION SCIENTIFQUE EXPANSIA (FR) 1992-12-29 US disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed
JP-S5716809-A DENTAL ADHESIVE COMPOSITION LION CORP 1982-01-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240139078-A1 DENTAL FILLING KIT DHX29, DHX35, DHX15 TGFBR1 4584/4885MME 3409/4885L3MBTL1 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.