Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.57 |
| ▸ | MMP8 | P22894 | 5/20 | 0.57 |
| ▸ | MMP1 | P03956 | 9/20 | 0.56 |
| ▸ | FCER2 | P06734 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 11/20 | 0.53 |
| ▸ | MMP3 | P08254 | 5/20 | 0.53 |
| ▸ | MMP7 | P09237 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346221 | 0.86 | TGFBR1 (0.57) | MMP9MMP8MMP14 | |
| SCHEMBL2258793 | 0.86 | TGFBR1 (0.57) | MMP9MMP8MMP14 | |
| SCHEMBL23376600 | 0.84 | CTSS (0.68) | MMP9MMP8MMP1FCER2MMP2 | |
| SCHEMBL13956933 | 0.84 | CTSS (0.68) | MMP9MMP8MMP1FCER2MMP2 | |
| SCHEMBL8374049 | 0.84 | FCER2 (0.50) | MMP9MMP8MMP1FCER2MMP14 | |
| SCHEMBL9561831 | 0.83 | MMP9 (0.74) | MMP9MMP8MMP2CTSSMMP14 | |
| SCHEMBL21988101 | 0.83 | MMP1 (0.63) | MMP9MMP8MMP1FCER2MMP2 | |
| SCHEMBL13524950 | 0.82 | ATM (0.62) | — | |
| SCHEMBL6218963 | 0.82 | ATM (0.62) | — | |
| SCHEMBL20669159 | 0.81 | MMP1 (0.61) | MMP9MMP8MMP1FCER2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375501-B1 | Process for enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo(4.3.0)nonane using simulated moving bed chromatography | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| EP-1375501-A1 | Process for enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo(4.3.0)nonane using simulated moving bed chromatography | Bayer Chemicals AG (DE) | 2004-01-02 | — | — | EP | disclosed |