Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562391 | 0.84 | NTRK1 (0.54) | GSK3BNTRK1HSD17B10GAALMNA | |
| SCHEMBL9562400 | 0.83 | PTPRC (0.68) | PTPRCESR1ESR2PTGS2LMNA | |
| SCHEMBL9562597 | 0.81 | PTPRC (0.59) | PTPRCESR1ESR2PTGS2GAA | |
| SCHEMBL9572013 | 0.80 | PTPRC (0.65) | PTPRCESR1ESR2PTGS2LMNA | |
| SCHEMBL7239290 | 0.75 | GAA (0.45) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL9572026 | 0.75 | ALDH1A1 (0.60) | PTPRCESR1ESR2PTGS2LMNA | |
| SCHEMBL9572001 | 0.74 | PTPRC (0.50) | PTPRCESR1ESR2PTGS2HSD17B10 | |
| SCHEMBL29634190 | 0.72 | KMT2A (0.54) | GSK3BHSD17B10GAALMNAKMT2A | |
| SCHEMBL26168119 | 0.72 | KMT2A (0.54) | GSK3BHSD17B10GAALMNAKMT2A | |
| SCHEMBL9561901 | 0.72 | CCR6 (0.56) | PTPRCHSD17B10GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |