Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562597 | 0.93 | PTPRC (0.59) | PTPRCCCR6HKDC1IMPDH2PTGS2 | |
| SCHEMBL9561901 | 0.92 | CCR6 (0.56) | PTPRCCCR6HKDC1IMPDH2HPGD | |
| SCHEMBL9572013 | 0.86 | PTPRC (0.65) | PTPRCPTGS2HPGDMAPTALDH1A1 | |
| SCHEMBL9561922 | 0.84 | CCR6 (0.51) | PTPRCCCR6HKDC1IMPDH2PTGS2 | |
| SCHEMBL9562400 | 0.83 | PTPRC (0.68) | PTPRCPTGS2HPGDMAPTALDH1A1 | |
| SCHEMBL9572023 | 0.82 | MEN1 (0.51) | PTPRCCCR6HKDC1IMPDH2HPGD | |
| SCHEMBL15797114 | 0.81 | PRKCB (0.54) | CCR6HKDC1IMPDH2PTGS2HPGD | |
| SCHEMBL15797025 | 0.81 | IMPDH2 (0.49) | CCR6HKDC1IMPDH2PTGS2HPGD | |
| SCHEMBL9572005 | 0.80 | CCR6 (0.45) | CCR6HKDC1IMPDH2HPGDMAPT | |
| SCHEMBL17210892 | 0.79 | DDX3X (0.48) | CCR6HKDC1IMPDH2PTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |