Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572001 | 0.93 | PTPRC (0.50) | PTPRCPTGS2ESR1ESR2CCR6 | |
| SCHEMBL9561901 | 0.91 | CCR6 (0.56) | PTPRCCCR6HKDC1IMPDH2GAA | |
| SCHEMBL9562400 | 0.91 | PTPRC (0.68) | PTPRCPTGS2ESR1ESR2 | |
| SCHEMBL9572013 | 0.88 | PTPRC (0.65) | PTPRCPTGS2ESR1ESR2 | |
| SCHEMBL29094061 | 0.86 | PTGS2 (0.55) | PTPRCPTGS2ESR1ESR2CCR6 | |
| SCHEMBL6252574 | 0.84 | PTGS2 (0.53) | PTPRCPTGS2ESR1ESR2CCR6 | |
| SCHEMBL7682255 | 0.84 | CCR6 (0.57) | PTPRCPTGS2ESR1ESR2CCR6 | |
| SCHEMBL9561922 | 0.82 | CCR6 (0.51) | PTPRCPTGS2CCR6HKDC1IMPDH2 | |
| SCHEMBL9572026 | 0.82 | ALDH1A1 (0.60) | PTPRCPTGS2ESR1ESR2 | |
| SCHEMBL9572023 | 0.81 | MEN1 (0.51) | PTPRCCCR6HKDC1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |