Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PRF1 | P14222 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL9561887 | 0.80 | MAPT (0.57) | ALDH1A1MAPTRAB9AAPPTDP1 | |
| SCHEMBL1918267 | 0.76 | MAPK14 (0.55) | ALDH1A1MAPTRAB9AAPPTDP1 | |
| SCHEMBL7249247 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTRAB9AAPPTDP1 | |
| SCHEMBL3142640 | 0.69 | MAPT (0.72) | ALDH1A1MAPTRAB9AAPPTDP1 | |
| SCHEMBL490119 | 0.69 | AKR1B1 (0.58) | ALDH1A1MAPTRAB9AAPPTDP1 | |
| SCHEMBL30944682 | 0.69 | MAOA (0.53) | ALDH1A1MAPTRAB9ATDP1L3MBTL1 | |
| SCHEMBL9395404 | 0.69 | MAOA (0.53) | ALDH1A1MAPTRAB9ATDP1L3MBTL1 | |
| SCHEMBL17637909 | 0.69 | PTPRC (0.59) | MAPTRAB9ATDP1L3MBTL1MAOB | |
| SCHEMBL15767065 | 0.69 | MAPK14 (0.40) | APPTDP1L3MBTL1HTR2BMAOB | |
| SCHEMBL7246016 | 0.68 | TDP1 (0.64) | ALDH1A1MAPTRAB9AAPPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409406-B1 | ARYL-SUBSTITUTED AMINE DERIVATIVES USEFUL IN CANCER THERAPY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-08 | — | — | EP | disclosed |