Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094061 | 0.84 | PTGS2 (0.55) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL9562597 | 0.84 | PTPRC (0.59) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL6252574 | 0.83 | PTGS2 (0.53) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL18392295 | 0.82 | ESR1 (0.59) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL15797025 | 0.78 | IMPDH2 (0.49) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL15797114 | 0.78 | PRKCB (0.54) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL29094070 | 0.77 | CCR6 (0.55) | CCR6HKDC1IMPDH2GAA | |
| SCHEMBL17383846 | 0.77 | IMPDH2 (0.73) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL9572001 | 0.77 | PTPRC (0.50) | CCR6HKDC1ESR1ESR2PTGS2 | |
| SCHEMBL17210892 | 0.77 | DDX3X (0.48) | CCR6HKDC1ESR1ESR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376529-B1 | INSULIN DISEASES; ANTIDIABETIC AGENTS | SUGEN, INC. | 2002-04-23 | — | — | US | disclosed |