SCHEMBL9562982

SCHEMBL9562982

COc1cc(OC)nc(SS2(CC(=O)OCc3ccccc3)CCCS2)n1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
L3MBTL1 Q9Y468 4/20 0.34
MAPK1 P28482 1/20 0.34
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
TSHR P16473 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
ADORA3 P0DMS8 1/20 0.33
ADORA1 P30542 1/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562987 0.84 ADORA3 (0.36) ALDH1A1ADORA3ADORA1KDM4E
SCHEMBL9563039 0.83 ADORA3 (0.36) ALDH1A1L3MBTL1HSD17B10ADORA3ADORA1
SCHEMBL9563013 0.81 ADORA3 (0.36) ALDH1A1ADORA3ADORA1KDM4E
SCHEMBL9562983 0.71 L3MBTL1 (0.37) ALDH1A1L3MBTL1MAPK1PTGESALOX5
SCHEMBL9562984 0.67 PTGES (0.43) ALDH1A1PTGESALOX5
SCHEMBL9562990 0.67 PTGES (0.47) ALDH1A1PTGESALOX5
SCHEMBL8406394 0.66 TDP1 (0.51) ALDH1A1L3MBTL1MAPK1TSHRSMN1; SMN2
SCHEMBL9562986 0.65 PTGES (0.40) ALDH1A1PTGESALOX5TSHR
SCHEMBL8723367 0.64 MEN1 (0.48) ALDH1A1HSD17B10MAPTGLATDP1
SCHEMBL21091351 0.60 TDP1 (0.46) ALDH1A1L3MBTL1TSHRSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573837-A1 Acetal-containing pyrimidinylthioaliphatic acid derivatives useful as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1993-12-15 EP disclosed