SCHEMBL9563015

SCHEMBL9563015

PC(c1ccccc1)(c1ccccc1)c1ccccc1Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.41
CALM1 P0DP23 1/20 0.41
BCL2 P10415 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALOX5 P09917 1/20 0.35
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
DRD2 P14416 1/20 0.33
DRD1 P21728 1/20 0.33
DRD4 P21917 1/20 0.33
DRD5 P21918 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ATM Q13315 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL29076662 0.87 LTA4H (0.35) HTR2ASMN1; SMN2MEN1KMT2AKDM4E
Bromide SCHEMBL29076674 0.87 KEAP1 (0.50) BCL2BCL2L1ALOX5ALDH1A1CYP3A4
Bromide SCHEMBL29076687 0.83 TAAR1 (0.36) MEN1KMT2A
Bromide SCHEMBL29076675 0.83 ALOX5 (0.41) BCL2BCL2L1CYP1A2ALOX5DRD2
Bromide SCHEMBL29076663 0.79 TAAR1 (0.36)
Bromide SCHEMBL29076668 0.79 HSPA5 (0.53) KDM4EALDH1A1HIF1A
SCHEMBL3435481 0.77 KCNN4 (0.50) HTR2ACALM1BCL2BCL2L1CYP1A2
SCHEMBL10900432 0.77 HTR2A (0.41) HTR2ACALM1BCL2BCL2L1DRD2
SCHEMBL1368134 0.76 KCNN4 (0.41) CYP1A2CYP2C9CYP2C19ALDH1A1CYP3A4
SCHEMBL3404551 0.76 CYP1A2 (0.42) HTR2ACALM1BCL2BCL2L1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561033-A1 Polymeric phoshonium salts providng enhanced chemiluminescence from 1,2-dioxetanes LUMIGEN, INC. (US) 1993-09-22 EP claimed