Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563203 | 0.91 | SLC6A2 (0.46) | CHRM3ADRB2BCHESLC6A2CYP2D6 | |
| SCHEMBL9563335 | 0.87 | BCHE (0.43) | CHRM3ADRB2BCHESLC6A2CHRM2 | |
| SCHEMBL9563318 | 0.84 | HTR1A (0.41) | CCR5CHRM3BCHESLC6A2CYP2D6 | |
| SCHEMBL9563259 | 0.82 | MEN1 (0.35) | SLC6A2CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9563279 | 0.82 | BCHE (0.42) | CCR5CHRM3BCHESLC6A2CYP2D6 | |
| SCHEMBL9563283 | 0.81 | GRM5 (0.36) | CHRM3ADRB2SLC6A2CYP2D6CHRM2 | |
| SCHEMBL9563278 | 0.81 | GRM5 (0.36) | CHRM3ADRB2SLC6A2CYP2D6CHRM2 | |
| SCHEMBL9563313 | 0.81 | GRM5 (0.36) | CHRM3ADRB2SLC6A2CYP2D6CHRM2 | |
| SCHEMBL9563213 | 0.81 | HTR7 (0.40) | CHRM3ADRB2BCHEHTR1ADRD2 | |
| SCHEMBL9563260 | 0.79 | CHRM3 (0.39) | CHRM3ADRB2BCHEHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |