Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 6/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563291 | 0.91 | CYP2D6 (0.43) | MEN1KMT2AHTR1ASCN1ASCN8A | |
| SCHEMBL9563335 | 0.87 | BCHE (0.43) | HTR1ADRD2HTR6SLC6A2CHRM2 | |
| SCHEMBL9563250 | 0.84 | SCN8A (0.36) | MEN1KMT2AHTR1ASCN1ASCN8A | |
| SCHEMBL9563336 | 0.84 | CYP2D6 (0.39) | HTR1ACYP2D6SLC6A2CHRM2ADRA2A | |
| SCHEMBL9563187 | 0.82 | CCR5 (0.38) | MEN1KMT2AHTR1ADRD2HTR6 | |
| SCHEMBL9563257 | 0.82 | CYP2D6 (0.40) | ALDH1A1KMT2ASMN1; SMN2HTR1ACYP2D6 | |
| SCHEMBL9563283 | 0.81 | GRM5 (0.36) | MEN1ALDH1A1KMT2AHTR1ACYP2D6 | |
| SCHEMBL9563278 | 0.81 | GRM5 (0.36) | MEN1ALDH1A1KMT2AHTR1ACYP2D6 | |
| SCHEMBL9563313 | 0.81 | GRM5 (0.36) | MEN1ALDH1A1KMT2AHTR1ACYP2D6 | |
| SCHEMBL9563213 | 0.81 | HTR7 (0.40) | ALDH1A1HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |