Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 9/20 | 0.36 |
| ▸ | SCN1A | P35498 | 6/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563291 | 0.89 | CYP2D6 (0.43) | SCN8ASCN1AHTR1ACYP2D6SLC6A2 | |
| SCHEMBL9563304 | 0.86 | BCHE (0.41) | ADRB3HTR1ASLC6A2LMNACHRM2 | |
| SCHEMBL9563259 | 0.84 | MEN1 (0.35) | SCN8ASCN1AHTR1ACYP2D6SLC6A2 | |
| SCHEMBL9565887 | 0.84 | BCHE (0.45) | ADRB3HTR1ACYP2D6SLC6A2MEN1 | |
| SCHEMBL9563231 | 0.83 | DRD4 (0.37) | ADRB3PRMT5HTR1ACYP2D6SLC6A2 | |
| SCHEMBL9563322 | 0.83 | HTR1A (0.36) | SCN8ASCN1AHTR1ACYP2D6SLC6A2 | |
| SCHEMBL9563216 | 0.81 | NPC1 (0.40) | CYP2D6MEN1LMNAKMT2A | |
| SCHEMBL9563351 | 0.80 | PRMT5 (0.34) | ADRB3PRMT5HTR1ACYP2D6SLC6A2 | |
| SCHEMBL9563249 | 0.80 | PRMT5 (0.34) | ADRB3PRMT5HTR1ACYP2D6SLC6A2 | |
| SCHEMBL9563258 | 0.80 | PRMT5 (0.34) | ADRB3PRMT5HTR1ACYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |