Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763479 | 0.83 | KDM4E (0.51) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL27467998 | 0.81 | GAA (0.49) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL27690792 | 0.79 | KDM4E (0.47) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL23135844 | 0.77 | FAAH (0.54) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL29811285 | 0.77 | ALDH1A1 (0.57) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL2632301 | 0.77 | ALDH1A1 (0.57) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7665723 | 0.76 | KDM4E (0.47) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL23135448 | 0.75 | FAAH (0.58) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL2973540 | 0.75 | FAAH (0.42) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3704245 | 0.75 | L3MBTL1 (0.56) | KDM4EGAAL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383091-B1 | Insecticidally active nitro compounds | BAYER AGROCHEM KK (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-5204359-A | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5084467-A | INSECTICIDALLY ACTIVE NITRO GUANIDINE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0383091-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-08-22 | — | — | EP | disclosed |