Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131735 | 0.79 | SLC10A2 (0.41) | SLC10A2L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL7819852 | 0.78 | WHR1 (0.48) | L3MBTL1KDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9181338 | 0.70 | SLC10A2 (0.47) | SLC10A2KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7489529 | 0.70 | ALDH1A1 (0.43) | SLC10A2L3MBTL1KDM4EALDH1A1TDP1 | |
| SCHEMBL8884921 | 0.64 | KDM4E (0.48) | L3MBTL1KDM4EALDH1A1HPGDPDGFRB | |
| SCHEMBL4291890 | 0.64 | ALDH1A1 (0.50) | SLC10A2L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7820197 | 0.64 | PDE4A (0.48) | L3MBTL1KDM4EALDH1A1HPGDPDGFRB | |
| SCHEMBL7825968 | 0.64 | WHR1 (0.46) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8138601 | 0.63 | WHR1 (0.42) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14544751 | 0.62 | PDE4A (0.51) | L3MBTL1KDM4EALDH1A1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-A1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |