Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490464 | 0.86 | LMNA (0.41) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL7487377 | 0.84 | LMNA (0.40) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| Dimethylamine SCHEMBL7490478 | 0.81 | POLB (0.44) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| Diethylamine SCHEMBL7488798 | 0.81 | MAPT (0.42) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL7819852 | 0.72 | WHR1 (0.48) | ALDH1A1KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL7493208 | 0.71 | SLC10A2 (0.50) | ALDH1A1KDM4EMAPTGAASMN1; SMN2 | |
| SCHEMBL9563393 | 0.70 | SLC10A2 (0.49) | ALDH1A1KDM4ETDP1LMNAMAPT | |
| Diethylamine SCHEMBL7484722 | 0.67 | ABCG2 (0.51) | ALDH1A1LMNAMAPTGAASLC10A2 | |
| SCHEMBL10690098 | 0.63 | L3MBTL1 (0.51) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL11754747 | 0.63 | L3MBTL1 (0.48) | ALDH1A1KDM4ETDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0791000-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014319-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |