Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 10/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | PI4KA | P42356 | 2/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563483 | 0.78 | AHCY (0.60) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9563488 | 0.78 | AHCY (0.60) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9563489 | 0.74 | ADORA2A (0.48) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL6158904 | 0.73 | AHCY (0.76) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1798270 | 0.72 | ADORA2A (0.72) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL2561529 | 0.72 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL15577353 | 0.70 | AHCY (0.70) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9563459 | 0.69 | ADORA2A (0.60) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9285391 | 0.68 | FGFR1 (0.62) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1733018 | 0.68 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |