Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | PI4KA | P42356 | 3/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563482 | 0.81 | CYP3A4 (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL9563486 | 0.74 | AHCY (0.55) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7199253 | 0.73 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1673251 | 0.70 | EGFR (0.70) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL17165347 | 0.70 | EGFR (0.66) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL27713663 | 0.69 | EGFR (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6694591 | 0.69 | EGFR (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL9435719 | 0.69 | PI4KA (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL13662886 | 0.68 | SLC22A6 (0.63) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12126374 | 0.68 | ADORA2A (0.54) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |