SCHEMBL9563607

SCHEMBL9563607

C=C[Si](C)(CCl)c1ccccc1C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.33
NOTUM Q6P988 1/20 0.31
IDO1 P14902 2/20 0.31
HTT P42858 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
C1R P00736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563585 0.85 HTT (0.31) HTT
SCHEMBL9563536 0.84 HTT (0.30) HTT
SCHEMBL9563587 0.84 HTT (0.30) HTT
SCHEMBL9563599 0.84 HTT (0.30) HTT
SCHEMBL29214153 0.78 HSD11B1 (0.37) HSD11B1NOTUMNR1H2NR1H3C1R
SCHEMBL7519289 0.78 IDO1 (0.39) HSD11B1NOTUMIDO1HTTNR1H2
SCHEMBL2295972 0.74 HSD11B1 (0.42) HSD11B1NOTUMIDO1C1R
SCHEMBL30626928 0.74 HSD11B1 (0.42) HSD11B1NOTUMIDO1C1R
SCHEMBL29214119 0.73 ALDH1A1 (0.35) HSD11B1NOTUMIDO1C1R
SCHEMBL29214141 0.73 ALDH1A1 (0.35) HSD11B1NOTUMIDO1C1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524829-A1 Novel silane compound, process of preparing the same and plant growth regulator containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-01-27 EP disclosed