Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626928 | 1.00 | HSD11B1 (0.42) | HSD11B1IDO1NOTUMALDH1A1TDP1 | |
| SCHEMBL1052795 | 0.86 | HSD11B1 (0.42) | HSD11B1IDO1NOTUMALDH1A1TDP1 | |
| SCHEMBL7519289 | 0.81 | IDO1 (0.39) | HSD11B1IDO1NOTUMALDH1A1TDP1 | |
| SCHEMBL19365961 | 0.80 | NOTUM (0.44) | HSD11B1NOTUMALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL19405518 | 0.79 | HSD11B1 (0.38) | HSD11B1NOTUMALDH1A1TDP1POLB | |
| Bromide SCHEMBL19405666 | 0.79 | HSD11B1 (0.42) | HSD11B1NOTUMALDH1A1TDP1POLB | |
| Bromide SCHEMBL19405537 | 0.79 | HSD11B1 (0.38) | HSD11B1IDO1NOTUMALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL19405387 | 0.79 | HSD11B1 (0.42) | HSD11B1NOTUMALDH1A1TDP1POLB | |
| SCHEMBL25456416 | 0.78 | ALDH1A1 (0.46) | IDO1ALDH1A1TDP1POLBLMNA | |
| SCHEMBL29214153 | 0.77 | HSD11B1 (0.37) | HSD11B1NOTUMALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947685-A | Method for synthesizing N, N-diaryl-O-allylhydroxylamine compound from nitroarene | 安徽中烟工业有限责任公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-3352281-B1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY | ADEKA CORP (JP) | 2021-08-11 | — | — | EP | disclosed |
| US-10734684-B2 | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery | ADEKA CORPORATION (JP) | 2020-08-04 | — | — | US | disclosed |
| US-10388989-B2 | Non-aqueous electrolyte, and non-aqueous electrolyte secondary cell | ADEKA CORPORATION (JP) | 2019-08-20 | — | — | US | disclosed |
| US-20180226683-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROPLYTE SECONDARY BATTERY | ADKEA CORPORATION (JP) | 2018-08-09 | — | — | US | disclosed |
| US-20180226683-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROPLYTE SECONDARY BATTERY | ADKEA CORPORATION (JP) | 2018-08-09 | — | — | US | disclosed |
| EP-3352281-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | Adeka Corporation (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-20180026304-A1 | NON-AQUEOUS ELECTROLYTE, AND NON-AQUEOUS ELECTROLYTE SECONDARY CELL | ADEKA CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20180026304-A1 | NON-AQUEOUS ELECTROLYTE, AND NON-AQUEOUS ELECTROLYTE SECONDARY CELL | ADEKA CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20160336621-A1 | NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY | ADEKA CORPORATION (JP) | 2016-11-17 | — | — | US | disclosed |
| WO-2013017374-A1 | ANTI -INFLAMMATORY STEROIDS CONDENSED IN POSITION 16,17 WITH PYRROLIDINE RING | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-02-07 | — | — | WO | disclosed |
| US-20130035320-A1 | PYRROLIDINE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-02-07 | — | — | US | disclosed |
| EP-2531516-A2 | PREGNANE COMPOUNDS CONDENSED IN POSITION 16,17 WITH A PYROLIDINE RING WITH GLUCOCORTICOID ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2012-12-12 | — | — | EP | disclosed |
| US-20110201580-A1 | PYRROLIDINE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-08-18 | — | — | US | disclosed |
| WO-2011095535-A2 | PYRROLIDINE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-08-11 | — | — | WO | disclosed |
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180226683-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROPLYTE SECONDARY BATTERY | SLC9A1, SLC8A1, KCNN1 | HSD11B1 1977/4885IDO1 2533/4885NOTUM 1196/4885 |
| US-10734684-B2 | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery | KCNN1, KCNN2, SLC9A1 | HSD11B1 882/4885IDO1 2262/4885NOTUM 1268/4885 |
| US-20130035320-A1 | PYRROLIDINE DERIVATIVES | NR3C1, TSLP, PTGS1 | HSD11B1 60/4885IDO1 131/4885NOTUM 1005/4885 |
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | HSD11B1 650/4885IDO1 112/4885NOTUM 2117/4885 |
| US-20110201580-A1 | PYRROLIDINE DERIVATIVES | IL5, TSLP, NR3C1 | HSD11B1 38/4885IDO1 298/4885NOTUM 370/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | HSD11B1 654/4885IDO1 74/4885NOTUM 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.