Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24693242 | 0.97 | — | — | |
| SCHEMBL9563864 | 0.80 | SLC6A3 (0.37) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL28090989 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL28091490 | 0.75 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL608461 | 0.75 | SLC6A4 (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL20547958 | 0.75 | HRH3 (0.38) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL288088 | 0.72 | FDPS (0.33) | SLC6A4SLC6A3SLC6A2FDPS | |
| SCHEMBL19334589 | 0.72 | SLC6A4 (0.39) | SLC6A4SLC6A3FDPS | |
| SCHEMBL3309623 | 0.72 | SLC6A4 (0.39) | SLC6A4SLC6A3FDPS | |
| SCHEMBL21862178 | 0.70 | CYP3A4 (0.37) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960246-A | Novel cyclosporin derivatives and use thereof | 美国科技环球有限公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-103249424-B | For treating and preventing the novel cyclosporin derivatives of virus infection | 河北鲲翔济世医药科技有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-8153660-B2 | Piperidyl-propane-thiol CCR3 modulators | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-10 | — | — | US | disclosed |
| US-8153660-B2 | Piperidyl-propane-thiol CCR3 modulators | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-10 | — | — | US | disclosed |
| US-8148403-B2 | Substituted piperidyl-propane-thiols | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-03 | — | — | US | disclosed |
| US-8148403-B2 | Substituted piperidyl-propane-thiols | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-03 | — | — | US | disclosed |
| US-8148403-B2 | Substituted piperidyl-propane-thiols | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-03 | — | — | US | disclosed |
| EP-2079725-B1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INT (DE) | 2011-12-14 | — | — | EP | disclosed |
| EP-2079725-B1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INT (DE) | 2011-12-14 | — | — | EP | disclosed |
| EP-2079731-B1 | NOVEL SUBSTITUTED PIPERIDYL-PROPANE-THIOLS | BOEHRINGER INGELHEIM INT (DE) | 2011-09-14 | — | — | EP | disclosed |
| US-20100317634-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20100317634-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-2079731-A1 | NOVEL SUBSTITUTED PIPERIDYL-PROPANE-THIOLS | Boehringer Ingelheim International GmbH (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-2079725-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | Boehringer Ingelheim International GmbH (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-2079725-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | Boehringer Ingelheim International GmbH (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-2079731-A1 | NOVEL SUBSTITUTED PIPERIDYL-PROPANE-THIOLS | Boehringer Ingelheim International GmbH (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008049875-A1 | NOVEL SUBSTITUTED PIPERIDYL-PROPANE-THIOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008049875-A1 | NOVEL SUBSTITUTED PIPERIDYL-PROPANE-THIOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008049874-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008049874-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317634-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | CCR3, CCR1, CCRL2 | SLC6A4 1490/4885SLC6A3 592/4885SLC6A2 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.