Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969285 | 0.81 | ALDH1A1 (0.55) | IDO1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL2273408 | 0.81 | ALDH1A1 (0.55) | IDO1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL5901677 | 0.79 | ALDH1A1 (0.53) | IDO1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL2273405 | 0.79 | HTT (0.63) | IDO1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL18763976 | 0.76 | TAAR1 (0.52) | IDO1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL8134521 | 0.76 | ALDH1A1 (0.50) | IDO1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL3665017 | 0.76 | HTT (0.59) | IDO1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL27383168 | 0.75 | HTT (0.63) | ALDH1A1HTTPKMSMN1; SMN2KDM4E | |
| SCHEMBL8980476 | 0.75 | HTT (0.63) | ALDH1A1HTTPKMSMN1; SMN2KDM4E | |
| SCHEMBL12437151 | 0.75 | ALDH1A1 (0.49) | IDO1ALDH1A1HTTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |