Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969285 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HTTPKMCTBP2KDM4E | |
| SCHEMBL5901677 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HTTPKMKDM4ESMN1; SMN2 | |
| SCHEMBL9564020 | 0.81 | IDO1 (0.54) | ALDH1A1HTTPKMCTBP2KDM4E | |
| SCHEMBL7370074 | 0.80 | HTT (0.57) | HTTPKMCTBP2LTA4HKDM4E | |
| SCHEMBL498481 | 0.79 | F2RL1 (0.59) | ALDH1A1PKMKDM4EPOLBNPC1 | |
| SCHEMBL6581234 | 0.79 | LTA4H (0.53) | ALDH1A1HTTPKMLTA4HKDM4E | |
| SCHEMBL240822 | 0.78 | KDM4E (0.74) | ALDH1A1HTTPKMCTBP2KDM4E | |
| SCHEMBL8134521 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HTTPKMCTBP2KDM4E | |
| SCHEMBL18763976 | 0.78 | TAAR1 (0.52) | ALDH1A1HTTPKMCTBP2KDM4E | |
| SCHEMBL3665017 | 0.77 | HTT (0.59) | ALDH1A1HTTPKMCTBP2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | disclosed |
| US-9521845-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITÄT-MÜNCHEN (DE) | 2016-12-20 | — | — | US | disclosed |
| CN-105652595-A | Black photosensitive resin composition, black matrix and image display device | 东友精细化工有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-06-12 | — | — | US | disclosed |
| CN-101434682-B | Polymer resin composition | SUMITOMO CHEMICAL CO | 2014-04-09 | — | — | CN | disclosed |
| US-8669283-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-03-11 | — | — | US | disclosed |
| US-8563598-B2 | — | — | 2013-10-22 | — | — | US | disclosed |
| CN-101121825-B | Resin composition capable of polymerizing | SUMITOMO CO LTD | 2012-07-18 | — | — | CN | disclosed |
| US-20110196027-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN | 2011-08-11 | — | — | US | disclosed |
| EP-2254574-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | Ludwig-Maximilians-Universität München (DE) | 2010-12-01 | — | — | EP | disclosed |
| CN-101735400-A | Curable resin composition | SUMITOMO CHEMICAL CO | 2010-06-16 | — | — | CN | disclosed |
| WO-2009106211-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2009-09-03 | — | — | WO | disclosed |
| CN-101434682-A | Polymer resin composition | SUMITOMO CHEMICAL CO (JP) | 2009-05-20 | — | — | CN | disclosed |
| CN-101121825-A | Resin composition capable of polymerizing | SUMITOMO CHEMICAL CO (JP) | 2008-02-13 | — | — | CN | disclosed |
| US-4571437-A | CATALYTIC HYDROGENATION REDUCTION AND REARRANGEMENT OF NITROBENZENE IN PRESENCE OF SULFUR COMPOUND | MALLINCKRODT, INC. (US) | 1986-02-18 | — | — | US | disclosed |
| US-4183951-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1980-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | ALDH1A1 4077/4885HTT 2856/4885PKM 3751/4885 |
| US-20110196027-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | ALDH1A1 4077/4885HTT 2856/4885PKM 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.