Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | F10 | P00742 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22462352 | 0.87 | F10 (0.68) | F2F10CYP1A2F3MAPT | |
| SCHEMBL22462351 | 0.87 | F10 (0.68) | F2F10CYP1A2F3MAPT | |
| Diethylamine SCHEMBL5688882 | 0.83 | CYP1A2 (0.72) | CYP1A2F3MAPTRAB9AALDH1A1 | |
| Diethylamine SCHEMBL8780613 | 0.80 | CYP1A2 (0.53) | CYP1A2F3MAPTRAB9AALDH1A1 | |
| Diethylamine SCHEMBL8377307 | 0.79 | MAPT (0.55) | CYP1A2F3MAPTRAB9AALDH1A1 | |
| SCHEMBL6805432 | 0.79 | ALDH1A1 (0.57) | F2F10CYP1A2MAPTALDH1A1 | |
| SCHEMBL6805427 | 0.79 | ALDH1A1 (0.57) | F2F10CYP1A2MAPTALDH1A1 | |
| Diethylamine SCHEMBL8377295 | 0.78 | MAPT (0.55) | CYP1A2F3MAPTRAB9AALDH1A1 | |
| Diethylamine SCHEMBL8780594 | 0.76 | ACHE (0.67) | MAPTRAB9AALDH1A1HTTMAPK1 | |
| Diethylamine SCHEMBL8780601 | 0.75 | ALDH1A1 (0.52) | CYP1A2F3MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551697-A1 | Photoinitiator system and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |