Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN1 | O60741 | 2/20 | 0.40 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 3/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.38 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564411 | 0.85 | SCD (0.41) | HCN1HCN4RAB9ANPC1TSHR | |
| SCHEMBL9564357 | 0.84 | CYP2E1 (0.37) | HCN1HCN4RAB9ANPC1NOTUM | |
| SCHEMBL24620298 | 0.73 | MAPT (0.47) | HCN1HCN4NOTUMTSHRALDH1A1 | |
| SCHEMBL9564359 | 0.73 | HCN1 (0.39) | HCN1HCN4NPC1TSHRCYP1A2 | |
| SCHEMBL1160956 | 0.68 | DHFR (0.44) | HCN1HCN4RAB9ANPC1TSHR | |
| SCHEMBL12833872 | 0.67 | NOTUM (0.41) | RAB9ANPC1NOTUMS1PR1CYP1A2 | |
| SCHEMBL28762616 | 0.66 | NOTUM (0.43) | RAB9ANPC1NOTUMS1PR1TSHR | |
| SCHEMBL7454799 | 0.66 | MAPT (0.46) | HCN1HCN4CSNK1DMAPK11MAPK14 | |
| SCHEMBL24620294 | 0.65 | CYP2D6 (0.55) | HCN1HCN4TSHRCYP1A2CYP2D6 | |
| SCHEMBL7360410 | 0.65 | CHRM5 (0.52) | RAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |