Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28930129 | 0.70 | NPC1 (0.70) | MEN1KMT2A | |
| SCHEMBL9255995 | 0.68 | MAPT (0.44) | FYNPDGFRAMAPKAPK2AURKBCSNK1G1 | |
| SCHEMBL9256004 | 0.68 | MAPT (0.44) | FYNPDGFRAMAPKAPK2AURKBCSNK1G1 | |
| SCHEMBL4145079 | 0.68 | CYP1A2 (0.45) | PDGFRATSHRALDH1A1KMT2A | |
| SCHEMBL17560828 | 0.65 | HTR7 (0.70) | PLK1NUDT1EGFR | |
| SCHEMBL4145075 | 0.65 | CYP2A6 (0.42) | PDGFRA | |
| SCHEMBL1179640 | 0.64 | ALDH1A1 (0.64) | FYNALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL9564368 | 0.64 | HIF1A (0.44) | HDAC1 | |
| SCHEMBL17788517 | 0.63 | ALDH1A1 (0.45) | ALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL5755932 | 0.63 | PHF8 (0.51) | FYNPDGFRAMAPKAPK2AURKBCSNK1G1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |