Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | GPR39 | O43194 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422419 | 0.82 | HIF1A (0.49) | HIF1AVCPKDM4EATMMLLT1 | |
| SCHEMBL9564402 | 0.75 | VCP (0.49) | HIF1AVCPKDM4EATMMLLT1 | |
| SCHEMBL9564361 | 0.72 | RAB9A (0.49) | HIF1AVCPEPHX2 | |
| SCHEMBL9564375 | 0.72 | HIF1A (0.43) | HIF1AKDM4EATMMLLT1MAPK1 | |
| SCHEMBL9911636 | 0.69 | MLLT1 (0.63) | MLLT1 | |
| SCHEMBL4136936 | 0.69 | NOTUM (0.62) | PRKDCHDAC3HDAC1PTPRSPIM1 | |
| SCHEMBL13096156 | 0.69 | HIF1A (0.50) | HIF1AKDM4EATMMLLT1MAPK1 | |
| SCHEMBL2943516 | 0.68 | FYN (0.67) | PIM1PIM2 | |
| SCHEMBL4145079 | 0.66 | CYP1A2 (0.45) | KDM4ERETCYP2A6 | |
| SCHEMBL1179640 | 0.66 | ALDH1A1 (0.64) | HDAC3HDAC1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |