Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422419 | 0.75 | HIF1A (0.49) | VCPSCD5EPHX2SCDTSHR | |
| SCHEMBL9564402 | 0.73 | VCP (0.49) | RAB9AVCPSMN1; SMN2KMT2ASCD5 | |
| SCHEMBL9564368 | 0.72 | HIF1A (0.44) | VCPEPHX2HIF1A | |
| SCHEMBL11934834 | 0.71 | PDPK1 (0.47) | VCPSMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL13438705 | 0.71 | PDPK1 (0.47) | VCPSMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL5024937 | 0.70 | ADORA2A (0.61) | VCP | |
| SCHEMBL5024974 | 0.70 | ADORA2A (0.56) | VCP | |
| SCHEMBL5016206 | 0.70 | ADORA2A (0.47) | RAB9AVCPALDH1A1LMNATP53 | |
| SCHEMBL1477034 | 0.68 | EPHX2 (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL20507209 | 0.68 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |