SCHEMBL1477034

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20507209	0.82	RAB9A (0.52)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL10274628	0.82	RAB9A (0.51)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL1474547	0.82	NOTUM (0.59)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL14948947	0.78	RAB9A (0.55)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL17790250	0.78	EPHX2 (0.53)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL1474304	0.76	ALDH1A1 (0.55)	RAB9ANPC1L3MBTL1ALDH1A1MAPT
	SCHEMBL17788637	0.74	EPHX2 (0.50)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL14946441	0.74	RAB9A (0.52)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL13863579	0.74	EPHX2 (0.42)	EPHX2RAB9ANPC1L3MBTL1ALDH1A1
	SCHEMBL1457325	0.74	NOTUM (0.68)	RAB9ANPC1L3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.