Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564345 | 1.00 | KDR (0.34) | KDRNPC1RAB9ALMNAMEN1 | |
| SCHEMBL9564362 | 0.77 | GSK3B (0.42) | KDRNPC1RAB9ALMNAMAPT | |
| SCHEMBL9564365 | 0.76 | KMT2A (0.43) | NPC1RAB9ALMNAMEN1ALDH1A1 | |
| SCHEMBL9564372 | 0.76 | KMT2A (0.43) | NPC1RAB9ALMNAMEN1ALDH1A1 | |
| SCHEMBL9564437 | 0.70 | L3MBTL1 (0.37) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9564440 | 0.70 | L3MBTL1 (0.37) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9564382 | 0.69 | KMT2A (0.44) | NPC1RAB9AMEN1ALDH1A1MAPT | |
| SCHEMBL9564369 | 0.69 | ALDH1A1 (0.49) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9564386 | 0.69 | DAO (0.41) | RAB9ALMNAMEN1ALDH1A1MAPT | |
| SCHEMBL9564392 | 0.68 | MAPT (0.49) | NPC1RAB9ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |