Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564370 | 1.00 | GAA (0.48) | GAALMNATSHRKDM4EMAPT | |
| SCHEMBL23204287 | 0.84 | MAPT (0.44) | GAATSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL9564382 | 0.79 | KMT2A (0.44) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL23162656 | 0.78 | MEN1 (0.52) | GAALMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL9564365 | 0.77 | KMT2A (0.43) | LMNAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL9564372 | 0.77 | KMT2A (0.43) | LMNAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL9564369 | 0.76 | ALDH1A1 (0.49) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9564413 | 0.74 | CES2 (0.40) | KDM4EMAPTMEN1KMT2AHPGD | |
| SCHEMBL9564422 | 0.74 | CES2 (0.40) | KDM4EMAPTMEN1KMT2AHPGD | |
| SCHEMBL9564371 | 0.74 | GAA (0.50) | GAALMNATSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |