Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564854 | 0.76 | ALDH1A1 (0.44) | PTGS1RXRARXRBGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL25237890 | 0.75 | EGLN1 (0.49) | EGLN1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9141792 | 0.75 | JAK3 (0.42) | PTGS2 | |
| SCHEMBL9564901 | 0.74 | PTGS1 (0.42) | PTGS1RXRARXRBRXRGSRC | |
| SCHEMBL29678121 | 0.71 | RXRA (0.50) | PTGS1RXRARXRBRXRGSRC | |
| SCHEMBL9141786 | 0.70 | TRPV1 (0.51) | — | |
| SCHEMBL9564959 | 0.67 | PTGS1 (0.40) | PTGS1 | |
| SCHEMBL889033 | 0.65 | HRH4 (0.52) | AGBL2 | |
| SCHEMBL5156156 | 0.65 | PTGS1 (0.59) | PTGS1RXRARXRB | |
| SCHEMBL12258207 | 0.64 | SRC (0.65) | PTGS1RXRARXRBRXRGSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |