Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564959 | 0.85 | PTGS1 (0.40) | PTGS1SUCNR1PTGDR2KDM4EMEN1 | |
| SCHEMBL9564742 | 0.78 | THRA (0.36) | PTGS1DGAT1RXRARXRBPTGDR2 | |
| SCHEMBL9564754 | 0.74 | PTGS1 (0.39) | PTGS1DGAT1RXRARXRBRXRG | |
| SCHEMBL13081603 | 0.71 | L3MBTL1 (0.47) | NTRK1NTRK3KDM4EMEN1KMT2A | |
| SCHEMBL29678121 | 0.71 | RXRA (0.50) | PTGS1RXRARXRBRXRGSRC | |
| SCHEMBL9564892 | 0.69 | EGLN1 (0.44) | PTGS1DGAT1 | |
| SCHEMBL5156156 | 0.68 | PTGS1 (0.59) | PTGS1RXRARXRBSUCNR1LMNA | |
| SCHEMBL10688710 | 0.68 | ADORA1 (0.52) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7495911 | 0.68 | ABCC4 (0.46) | PTGS1DGAT1RXRARXRBRXRG | |
| SCHEMBL20565701 | 0.66 | ALDH1A1 (0.42) | DGAT1PTGDR2KDM4ESRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |