Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565018 | 0.82 | KDM4E (0.40) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9564984 | 0.81 | KDM4E (0.39) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5200214 | 0.75 | NPSR1 (0.41) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20065121 | 0.68 | KMT2A (0.43) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5477906 | 0.67 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10407464 | 0.66 | MEN1 (0.38) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10407399 | 0.66 | MEN1 (0.38) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL18305810 | 0.65 | ALDH1A1 (0.39) | KDM4ENPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2743303 | 0.65 | EGLN1 (0.37) | KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL15082052 | 0.62 | EGLN1 (0.42) | KDM4ENPSR1ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |