Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564930 | 0.82 | KDM4E (0.40) | KDM4ENPSR1POLBALDH1A1L3MBTL1 | |
| SCHEMBL9564984 | 0.81 | KDM4E (0.39) | KDM4ENPSR1POLBALDH1A1L3MBTL1 | |
| SCHEMBL9564745 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1PKM | |
| SCHEMBL10407044 | 0.70 | MEN1 (0.49) | KDM4ENPSR1ALDH1A1LMNATP53 | |
| SCHEMBL10407399 | 0.69 | MEN1 (0.38) | KDM4ENPSR1POLBALDH1A1L3MBTL1 | |
| SCHEMBL5477906 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10407464 | 0.62 | MEN1 (0.38) | KDM4ENPSR1POLBALDH1A1L3MBTL1 | |
| SCHEMBL15082052 | 0.62 | EGLN1 (0.42) | KDM4ENPSR1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1158337 | 0.62 | TDP1 (0.34) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10772488 | 0.62 | HCAR2 (0.34) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |