Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564930 | 0.81 | KDM4E (0.40) | KDM4ENPSR1POLBKMT2AMEN1 | |
| SCHEMBL9565018 | 0.81 | KDM4E (0.40) | KDM4ENPSR1POLBKMT2AMEN1 | |
| SCHEMBL4574660 | 0.66 | HCAR2 (0.48) | NPSR1KMT2AMEN1HCAR2CYP2C9 | |
| SCHEMBL7518054 | 0.66 | HCAR2 (0.39) | KDM4EKMT2AMEN1HCAR2CYP2C9 | |
| SCHEMBL5477906 | 0.66 | ALDH1A1 (0.40) | KMT2AMEN1HCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1919221 | 0.62 | HCAR2 (0.39) | KMT2AMEN1HCAR2CYP2C9CYP2C19 | |
| SCHEMBL1026100 | 0.62 | ALDH1A1 (0.39) | KDM4EPOLBKMT2AMEN1HCAR2 | |
| SCHEMBL10407464 | 0.61 | MEN1 (0.38) | KDM4ENPSR1POLBKMT2AMEN1 | |
| SCHEMBL10407399 | 0.61 | MEN1 (0.38) | KDM4ENPSR1POLBKMT2AMEN1 | |
| SCHEMBL15082052 | 0.61 | EGLN1 (0.42) | KDM4ENPSR1HCAR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |